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Breast Cancer

 Breast cancer is the most common cancer diagnosed among US women. Air pollution is a pervasive mixture of chemicals containing carcinogenic compounds and chemicals with endocrine disrupting properties. There is epidemiologic evidence regarding the association between air pollution and breast cancer risk.

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Recent findings have identified seventeen studies evaluating the risk of breast cancer associated with air pollution. A higher risk of breast cancer has been associated with nitrogen dioxide (NO2) and nitrogen oxides (NOx) levels, both of which are proxies for traffic exposure. 

 

Hazardous air toxic levels and sources of indoor air pollution may also contribute to breast cancer risk. There is little existing evidence to support that the relationship between air pollution and breast cancer risk varies by either menopausal status at diagnosis or combined tumor hormone receptor subtype defined by the estrogen receptor (ER) and progesterone receptor (PR).

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Epidemiologic evidence to date suggests an association between breast cancer risk and NO2 and NOx, markers for traffic-related air pollution.